WWTR1 抗体
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北京 101111
Quick Overview for WWTR1 抗体 (ABIN2457959)
抗原
See all WWTR1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WWTR1.
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应用备注
- WWTR1 antibody can be used for detection of WWTR1 by ELISA at 1:62500. WWTR1 antibody can be used for detection of WWTR1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store WWTR1 antibody at -20 °C.
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- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
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别名
- WWTR1
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背景
- TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
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分子量
- 44 kDa
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基因ID
- 25937
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NCBI登录号
- NP_056287
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UniProt
- Q9GZV5
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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