Shugoshin 抗体
(3 references)Quick Overview for Shugoshin 抗体 (ABIN2452123)
抗原
See all Shugoshin (SGOL1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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过滤
- Sterile filtered
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anti-Shugoshin 1 (SGOL1) (AA 1-292) antibody
SGOL1 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Shugoshin 1 (SGOL1) (AA 260-439) antibodySGOL1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) (AA 1-292) antibodySGOL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) (AA 10-100) antibodySGOL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) (Internal Region) antibodySGOL1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) antibodySGOL1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) (AA 1-292) antibodySGOL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) (N-Term) antibodySGOL1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) (AA 395-444) antibodySGOL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Shugoshin 1 (SGOL1) (AA 260-439) antibodySGOL1 适用: 人, 小鼠 ELISA, WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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1) Western blotting: 1,000 fold dilution
2) Immunofluoresece staining: 100 fold dilution -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 1 mg/mL BSA, PBS ( pH 7.2), 50 % glycerol
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储存液
- Azide free
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储存条件
- -20 °C
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: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).
: "Shugoshin protects cohesin complexes at centromeres." in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 360, Issue 1455, pp. 515-21, discussion 521, (2005) (PubMed).
: "The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis." in: Nature, Vol. 427, Issue 6974, pp. 510-7, (2004) (PubMed).
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: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).
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- Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
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背景
- Shugoshin 1 (Sgo1), a meiosis-specific protein, protects centromeric Rec8 from degradation during first meiotic division (meiosis I) in fission yeast Schizosaccharomyces pombe. This protein appears at late prophase of meiosis I and is degraded at anaphase I. Heterochromatin protein Swi6 associates directly with Sgo1. A point mutation of Sgo1 (V242E), which abolishes the interaction with Swi6, impairs the centromeric localization and function of Sgo1. The forced centromeric localization of Sgo1 restores proper meiotic chromosome segregation in swi6 cells. Using this antibody in Western blotting, the band of 37 kD was observed in wild type S. pombe MP111 extract.
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UniProt
- Q9P7A0
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途径
- Maintenance of Protein Location
抗原
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