RAB27A 抗体
Our Local Distributor
北京 101111
Quick Overview for RAB27A 抗体 (ABIN2443836)
抗原
See all RAB27A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rab27a Rabbit Polyclonal Antibody
-
特异性
- The antibody recognizes the human Rab27a protein.
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- If reconstituted with deionized water in 100 μL: WB: 1:1000 (Recommended blocking solution: Donkey Serum 20 % ). IP: native conditions with 0.2 % TritonX-100. Optimal dilution has to be determined by the user.
-
缓冲液
- Lyophilized serum
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
-
有效期
- 24 months
-
-
- RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
-
别名
- Rab27a
-
背景
-
Ras-related protein Rab-27A, RAB27A, GS2, HsT18676, RAB27, RAM, member RAS oncogene family
Ras-related protein Rab-27a (Rab27a) belongs to the small GTPase superfamily. The protein is membrane-bound and is involved in protein transport and small GTPase-mediated signal transduction. Rab27a plays a role in cytotoxic granule exocytosis in lymphocytes. Rab27a is widely expressed with considerable expression in pancreatic islets and pituitary tissue, and low expression in the brain. Defects in RAB27A are a cause of Griscelli syndrome type 2 (GS2), a rare autosomal recessive disorder.
-
UniProt
- P51159
-
途径
- Peptide Hormone Metabolism
抗原
-