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RAB27A 抗体

The 兔 多克隆 anti-RAB27A antibody (ABIN2443836) specifically detects RAB27A in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN2443836
发货至: 中国
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Quick Overview for RAB27A 抗体 (ABIN2443836)

抗原

See all RAB27A 抗体
RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAB27A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 原理

    Rab27a Rabbit Polyclonal Antibody

    特异性

    The antibody recognizes the human Rab27a protein.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    If reconstituted with deionized water in 100 μL: WB: 1:1000 (Recommended blocking solution: Donkey Serum 20 % ). IP: native conditions with 0.2 % TritonX-100. Optimal dilution has to be determined by the user.

    缓冲液

    Lyophilized serum

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

    有效期

    24 months
  • 抗原

    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

    别名

    Rab27a

    背景

    Ras-related protein Rab-27A, RAB27A, GS2, HsT18676, RAB27, RAM, member RAS oncogene family

    Ras-related protein Rab-27a (Rab27a) belongs to the small GTPase superfamily. The protein is membrane-bound and is involved in protein transport and small GTPase-mediated signal transduction. Rab27a plays a role in cytotoxic granule exocytosis in lymphocytes. Rab27a is widely expressed with considerable expression in pancreatic islets and pituitary tissue, and low expression in the brain. Defects in RAB27A are a cause of Griscelli syndrome type 2 (GS2), a rare autosomal recessive disorder.

    UniProt

    P51159

    途径

    Peptide Hormone Metabolism
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