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CD31 抗体 (PE)

PECAM1 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-05 PE
产品编号 ABIN238443
发货至: 中国
  • 抗原 See all CD31 (PECAM1) 抗体
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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    小鼠
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    单克隆
    标记
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    This CD31 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    Size-exclusion chromatography
    免疫原
    Leukocytes of patient suffering from LGL-type leukaemia
    克隆位点
    MEM-05
    亚型
    IgG1
    Top Product
    Discover our top product PECAM1 Primary Antibody
  • 应用备注
    Suitable for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL ofwhole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2-8 °C for one month or at -20 °C for longer.
  • Soupene, Serikov, Kuypers: "Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells." in: Journal of lipid research, Vol. 49, Issue 5, pp. 1103-12, (2008) (PubMed).

  • 抗原
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    别名
    CD31 / PECAM1 (PECAM1 产品)
    别名
    CD31 antibody, CD31/EndoCAM antibody, GPIIA' antibody, PECA1 antibody, PECAM-1 antibody, endoCAM antibody, C85791 antibody, Cd31 antibody, Pecam antibody, platelet/endothelial cell adhesion molecule 1 antibody, platelet and endothelial cell adhesion molecule 1 antibody, pecam1 antibody, PECAM1 antibody, Pecam1 antibody
    背景
    CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in rebulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
    基因ID
    9606
    UniProt
    P16284
    途径
    Regulation of Actin Filament Polymerization
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