ERBB3 抗体
Quick Overview for ERBB3 抗体 (ABIN232941)
抗原
See all ERBB3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Does not block the binding of heregulin to c-erbB-31, has no effect on tyrosine kinase activity1, receptor internalization1, or tumorigenic growth of cells overexpressing the cerbB- 32. It is particularly well suited for immunoprecipitation of unoccupied as well as the occupied receptor1. Species cross-reactivity: human.
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纯化方法
- Protein A purified
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免疫原
- Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein.
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亚型
- IgG2a
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应用备注
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Approved: Flo, IF, IP
Usage: Suitable for use in Flow Cytometry, Immunofluorescence, Immunoprecipitation, Effect on Heregulin (NDF) Binding (Non-inhibitory) and Effect on Tumor Growth (Non-inhibitory). Not suitable for Western Blot. Immunoprecipitation: 2 μg/mg protein lysate. Use Protein A. Well suited for Immunoprecipitation of unoccupied as well as occupied receptor. Positive control: T47D cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Not recommended for: IHC-P, WB -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4.
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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别名
- HER3 / ERBB3
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背景
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Name/Gene ID: ERBB3
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: ERBB3, C-erbB-3, C-erbB3, ErbB-3, HER3, p85-sErbB3, p45-sErbB3, MDA-BF-1, ErbB3-S, LCCS2, p180-ErbB3 -
基因ID
- 2065
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UniProt
- P21860
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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