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Insulin Receptor 抗体 (Exon 7)

This anti-Insulin Receptor antibody is a 小鼠 单克隆 antibody detecting Insulin Receptor in ELISA, IP 和 Func. Suitable for 人.
产品编号 ABIN228599
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (Exon 7) (ABIN228599)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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ELISA, Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

83-14
  • 抗原表位

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    AA 469-592, Exon 7

    特异性

    Recognizes human Insulin receptor, alpha subunit. Inhibits insulin binding (~80 % ) and mimics insulin action. Weakly reacts with bovine, porcine and sheep. Does not react with rabbit, mouse and rat.

    纯化方法

    Protein A purified

    免疫原

    IM-9 lymphocytes followed by purified insulin receptor. MW of Antigen: 135kD. Epitope: aa469-592 (exon 7/8). Cellular Localization: Cell membrane.

    Type of Immunogen: Cells

    亚型

    IgG2a kappa
  • 应用备注

    Approved: ELISA, Func, IP

    Usage: Suitable for use in ELISA, Immunoprecipitation, Tyrosine Kinase Assay and Inhibition of insulin binding. May also be used as insulin-like agonist. ELISA: Both as capture and detection. Immunoprecipitation (Use Protein G): 2 μg/mg protein lysate. Tyrosine Kinase Assay: Antibody-mediated capture on microtiter plates. Positive control: IM-9 lymphocyte cells and Placenta. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    10 mM PBS,  pH 7.4. Glycerol free.

    储存液

    Azide free

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    Insulin Receptor (INSR)

    别名

    INSR / Insulin Receptor

    背景

    Name/Gene ID: INSR
    Subfamily: Insulin receptor
    Family: Protein Kinase

    Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

    基因ID

    3643

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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