CD40 Ligand 抗体
Quick Overview for CD40 Ligand 抗体 (ABIN226478)
抗原
See all CD40 Ligand (CD40LG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes CD154 (mouse CD40 ligand/gp39), Mr 39kD. Binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens.
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纯化方法
- Purified
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免疫原
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Activated mouse Th1 clone D1.6.
Type of Immunogen: Cells -
亚型
- IgG kappa
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应用备注
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Approved: Flo, Func, IP
Usage: Flow cytometry. Immunoprecipitation. In vivo and in vitro blockage of CD154 function. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- CD40 Ligand (CD40LG)
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别名
- CD40LG / CD40L / CD154
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背景
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Name/Gene ID: CD40LG
Family: TNF
Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein -
基因ID
- 959
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UniProt
- P29965
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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