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CD31 抗体

This anti-CD31 antibody is a 大鼠 单克隆 antibody detecting CD31 in FACS, IF 和 IP. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2191753
发货至: 中国

Quick Overview for CD31 抗体 (ABIN2191753)

抗原

See all CD31 (PECAM1) 抗体
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD31 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

MEC7-46
  • 过滤

    0.2 μm filtered
  • 应用备注

    For immunohistochemistry and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Positive Mouse t-end.1 cells control Negative L929 cells (Fibroblasts) control 1

    限制

    仅限研究用
  • 缓冲液

    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Xu, Zhang, Davison, Hu: "Circulating progenitor cells regenerate endothelium of vein graft atherosclerosis, which is diminished in ApoE-deficient mice." in: Circulation research, Vol. 93, Issue 8, pp. e76-86, (2003) (PubMed).

  • 抗原

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    别名

    Pecam-1

    背景

    The monoclonal antibody MEC7.46 recognizes the mouse form of the platelet-endothelial cell adhesion molecule (PECAM)-1 (CD31). PECAM-1 is a member of the immunoglobulin superfamily. This heavily glycosylated protein is found in the entire vascular endothelium of adult mice and functions in mediating cellular adhesion by heterophilic and homophilic mechanisms. PECAM-1 is detected within the lymphopoietic islands in the spleen of newborn (day 12) and in the bone marrow of adult mice. Capillary endothelial cells of adult mice also express PECAM-1. The reactivity of the monoclonal antibody MEC7.46 is restricted to the isoform of the molecule that is selectively expressed by endothelial cells. The antibody precipitates a 130 kDa molecule present on the membrane of endothelial cells of all mouse blood vessels both in normal, inflamed and tumor tissues. The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1. Staining of MEC7.46 can be seen on capillaries, veins, arteries and liver sinusoids. Aliases CD31, platelet-endothelial cell adhesion molecule-1 Immunogen Mouse t.end.1 cells (polyoma middle T (PmT)-transformed EC)

    途径

    Regulation of Actin Filament Polymerization
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