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CEA 抗体 (PE)

This anti-CEA antibody is a 小鼠 单克隆 antibody detecting CEA in WB. Suitable for 人.
产品编号 ABIN2172924
发货至: 中国

Quick Overview for CEA 抗体 (PE) (ABIN2172924)

抗原

See all CEA 抗体
CEA (Carcinoembryonic Antigen Gene Family (CEA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CEA antibody is conjugated to PE

应用范围

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Western Blotting (WB)

克隆位点

3G7
  • 交叉反应

    纯化方法

    Purified by Protein G.

    免疫原

    KLH conjugated synthetic peptide derived from Human CEA/CEACAM5

    亚型

    IgG
  • 应用备注

    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • 抗原

    CEA (Carcinoembryonic Antigen Gene Family (CEA))

    别名

    CEA

    背景

    Synonyms: Carcino Embryonic Antigen CEA, CEACAM 5, CEACAM-5, Carcinoembryonic antigen, Carcinoembryonic antigen related cell adhesion molecule 5, CD66e, CD66e antigen, CEA, CEACAM5, DKFZp781M2392, Meconium antigen 100.

    Background: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

    基因ID

    1048
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