CEA 抗体 (PE)
Quick Overview for CEA 抗体 (PE) (ABIN2172924)
抗原
See all CEA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified by Protein G.
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免疫原
- KLH conjugated synthetic peptide derived from Human CEA/CEACAM5
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亚型
- IgG
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应用备注
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FCM: (1:20-100)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- CEA (Carcinoembryonic Antigen Gene Family (CEA))
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别名
- CEA
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背景
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Synonyms: Carcino Embryonic Antigen CEA, CEACAM 5, CEACAM-5, Carcinoembryonic antigen, Carcinoembryonic antigen related cell adhesion molecule 5, CD66e, CD66e antigen, CEA, CEACAM5, DKFZp781M2392, Meconium antigen 100.
Background: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
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基因ID
- 1048
抗原
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