Estrogen Receptor alpha 抗体 (AA 1-21)
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Quick Overview for Estrogen Receptor alpha 抗体 (AA 1-21) (ABIN215829)
抗原
See all Estrogen Receptor alpha (ESR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-21
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特异性
- Recognizes human and rat endogenous ER alpha. Detects a band of ~64kD by Western blot. Does not cross-react with ER beta. This sequence is completely conserved in rat and mouse ER alpha and is highly conserved in sheep, porcine, canine, bovine and chicken ER alpha.
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预测反应
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Tamarin, Mouse, Rat, Hamster, Cat, Rabbit, Horse (100%) Panda, Bovine, Pig (95%) Sheep, Opossum (90%) Turkey, Chicken (86%).
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纯化方法
- Immunoaffinity purified
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免疫原
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Synthetic peptide corresponding to aa 1-21 (M1TMTLHTKASGMALLHQIQGN21) of N-terminal human ER (estrogen receptor ). This sequence is completely conserved in rat and mouse ER and is highly conserved in sheep, pig, dog, bovine and chicken ER. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Tamarin, Mouse, Rat, Hamster, Cat, Rabbit, Horse (100%), Panda, Bovine, Pig (95%), Sheep, Opossum (90%), Turkey, Chicken (86%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
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Approved: ICC, IHC, IHC-Fr, IHC-P, WB (1 μg/mL)
Usage: Suitable for use in Immunocytochemistry, Immunohistochemistry and Western Blot. Immunohistochemistry (frozen, paraffin sections):1-5 μg/mL. Western Blot:1 μg/mL. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Epitope-affinity purified IgG in PBS, 1 mg/mL BSA, 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short term: 4°C
Long term: -20°C.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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别名
- ER Alpha / Estrogen Receptor
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背景
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Name/Gene ID: ESR1
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha -
基因ID
- 2099
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UniProt
- P03372
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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