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Integrin beta 3 抗体 (FITC)

ITGB3 适用: 小鼠, 大鼠 FACS, IP 宿主: 仓鼠 Monoclonal FITC
产品编号 ABIN206762
发货至: 中国
  • 抗原 See all Integrin beta 3 (ITGB3) 抗体
    Integrin beta 3 (ITGB3)
    适用
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    小鼠, 大鼠
    宿主
    • 120
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    仓鼠
    克隆类型
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    单克隆
    标记
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    This Integrin beta 3 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
    纯化方法
    Protein G purified
    免疫原
    Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
    亚型
    IgG
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • 应用备注
    Approved: Flo (1:1 - 1:10), IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    说明

    Target Species of Antibody: Mouse

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    Integrin beta 3 (ITGB3)
    别名
    ITGB3 / Integrin Beta 3 / CD61 (ITGB3 产品)
    背景
    Name/Gene ID: ITGB3
    Family: Integrin

    Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3
    基因ID
    3690
    UniProt
    P05106
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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