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Integrin beta 3 抗体 (FITC)

This anti-Integrin beta 3 antibody is a 仓鼠 单克隆 antibody detecting Integrin beta 3 in FACS 和 IP. Suitable for 小鼠 和 大鼠.
产品编号 ABIN206762
发货至: 中国

Quick Overview for Integrin beta 3 抗体 (FITC) (ABIN206762)

抗原

See all Integrin beta 3 (ITGB3) 抗体
Integrin beta 3 (ITGB3)

适用

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小鼠, 大鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This Integrin beta 3 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP)
  • 特异性

    Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.

    纯化方法

    Protein G purified

    免疫原

    Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.

    亚型

    IgG
  • 应用备注

    Approved: Flo (1:1 - 1:10), IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    Integrin beta 3 (ITGB3)

    别名

    ITGB3 / Integrin Beta 3 / CD61

    背景

    Name/Gene ID: ITGB3
    Family: Integrin

    Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3

    基因ID

    3690

    UniProt

    P05106

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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