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C3 抗体

C3 适用: 人 ELISA, IHC, IHC (fro), FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN206674
发货至: 中国
  • 抗原 See all C3 抗体
    C3 (Complement Component 3 (C3))
    适用
    • 88
    • 54
    • 34
    • 5
    • 4
    • 4
    • 3
    • 3
    宿主
    • 68
    • 43
    • 26
    • 8
    • 7
    • 5
    小鼠
    克隆类型
    • 123
    • 33
    单克隆
    标记
    • 66
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    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
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    This C3 antibody is un-conjugated
    应用范围
    • 101
    • 49
    • 37
    • 33
    • 33
    • 29
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    ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    特异性
    Specific for human complement component 3d (C3d) neoantigen, a 33kD polypeptide fragment generated over the course of complement activation in which where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
    纯化方法
    Protein A purified
    免疫原
    Purified human C3d (neoantigen).
    亚型
    IgG1
    Top Product
    Discover our top product C3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Borate buffered saline, 0.1 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    C3 (Complement Component 3 (C3))
    别名
    Complement C3 (C3 产品)
    别名
    AHUS5 antibody, ARMD9 antibody, ASP antibody, C3a antibody, C3b antibody, CPAMD1 antibody, AI255234 antibody, HSE-MSF antibody, Plp antibody, C3 antibody, C3-1 antibody, sb:cb26 antibody, si:dkey-76b14.4 antibody, wu:fi34b03 antibody, wu:fj86e11 antibody, C3d antibody, asp antibody, cpamd1 antibody, c3 antibody, complement C3 antibody, complement component 3 antibody, complement component c3a, duplicate 1 antibody, complement component 3 L homeolog antibody, complement component C3 antibody, complement C3-like antibody, C3 antibody, c3a.1 antibody, c3.L antibody, LOC443475 antibody, c3 antibody, c3-1 antibody, LOC100060539 antibody
    背景
    Name/Gene ID: C3

    Synonyms: C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3
    基因ID
    718
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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