C3 抗体
Our Local Distributor
北京 101111
Quick Overview for C3 抗体 (ABIN206656)
抗原
See all C3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Recognizes 9 kD complement component 3a (C3a) which is present in the blood serum. C3a is generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3a and C3b, which is further degraded into iC3b and C3dg/C3d. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation. C3a mediates local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3a is expressed at significantly higher levels in colorectal cancer. Shows minimal reactivity with other complement proteins in radioimmunoassays and hemagglutination. Clone 10-21 has been reported to work in western blotting applications.
-
纯化方法
- Protein A purified
-
免疫原
- Native purified human C3a.
-
亚型
- IgG1
-
-
anti-Complement Component 3 (C3) (AA 1000-1326) antibody
C3 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1551-1663) antibodyC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (fro), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1644) antibodyC3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) (C-Term) antibodyC3 适用: 人 WB, IP, ICC, IF, IHC (p), ISub 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 23-300) antibodyC3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 965-1303) antibodyC3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1645) antibodyC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) antibodyC3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5355 unconjugated Recombinant Antibody
anti-Complement Component 3 (C3) antibodyKD Validated C3 适用: 人 WB 宿主: 兔 Monoclonal 23GB1285 unconjugated Recombinant Antibody
anti-Complement Component 3 (C3) antibodyC3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB2945 unconjugated
-
-
应用备注
- Approved: ELISA (1:1500 - 1:6000), WB
-
说明
-
Target Species of Antibody: Human
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Borate buffered saline, pH 8.2, 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
-
- C3 (Complement Component 3 (C3))
-
别名
- Complement C3
-
背景
-
Name/Gene ID: C3
Synonyms: C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3 -
基因ID
- 718
-
UniProt
- P01024
-
途径
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-
