EGF 抗体 (Extracellular Domain)
Quick Overview for EGF 抗体 (Extracellular Domain) (ABIN205919)
抗原
See all EGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Extracellular Domain
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特异性
- Recognizes human Epidermal Growth Factor, a potent stimulator and regulator of the proliferation of epidermal and epithelial cells, expressed by a variety of cells. The effects of EGF are initiated through tyrosine kinase activity, following the binding of EGF to the extracellular domain of the ~170 kD EGF receptor (EGFR), which also binds other EGF-like ligands with high affinity, including TGF-a (transforming growth factor alpha), VGF (vaccinia virus growth factor) and Betacellulin, expressed in the pancreas, small intestine and by certain tumor cells. Receptor activation through EGF binding triggers several signal transduction pathways, including the JAK/STAT and P13K/AKT pathways.
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纯化方法
- Purified
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免疫原
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Recombinant human EGF.
Type of Immunogen: Recombinant protein -
亚型
- IgG
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anti-Epidermal Growth Factor (EGF) (AA 974-1026) antibody
EGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C11 unconjugated
anti-Epidermal Growth Factor (EGF) antibodyEGF 适用: 人 WB, DB 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor (EGF) antibodyEGF 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 9D7F11 unconjugated
anti-Epidermal Growth Factor (EGF) (AA 690-720), (Center) antibodyEGF 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB16555 unconjugated
anti-Epidermal Growth Factor (EGF) (AA 609-751) antibodyEGF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor (EGF) antibodyEGF 适用: 小鼠 WB, ELISA, Neut 宿主: 山羊 Polyclonal unconjugated
anti-Epidermal Growth Factor (EGF) antibodyEGF 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Epidermal Growth Factor (EGF) (AA 974-1026) antibodyEGF 适用: 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor (EGF) (AA 1-30) antibodyEGF 适用: 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor (EGF) (AA 31-53) antibodyEGF 适用: 人 ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Approved: ELISA (0.5 - 2 μg/mL), Func (0.25 - 0.35 μg/mL), IHC, IHC-P (0.25 - 1 μg/mL), WB (0.1 - 0.2 μg/mL)
Usage: Immunohistochemistry: This product requires protein digestion pre-treatment of paraffin sections e. g. trypsin or pronase. Histology Positive Control Tissue: Human skin ELISA: LS-C42950 may be used in an indirect ELISA system or as a capture antibody in a sandwich ELISA for human EGF in combination with LS-C42951 as a detection reagent. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.
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浓度
- Lot specific
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缓冲液
- Lyophilized, PBS, pH 7.4.
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- EGF (Epidermal Growth Factor (EGF))
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别名
- EGF
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背景
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Name/Gene ID: EGF
Synonyms: EGF, Beta-urogastrone, HOMG4, URG, Epidermal growth factor, Pro-epidermal growth factor -
基因ID
- 1950
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
抗原
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