Insulin Receptor 抗体
Quick Overview for Insulin Receptor 抗体 (ABIN201098)
抗原
See all Insulin Receptor (INSR) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes a protein of 135kD, identified as the alpha subunit of human insulin receptor (IR). Its epitope localizes in exon 7/8 and shows no cross-reactivity with IGF-receptors. Species cross-reactivity: Human, bovine, porcine and sheep. Weakly reacts with rabbit. Does not react with mouse or rat.
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纯化方法
- Protein G purified
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免疫原
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IM-9 lymphocytes followed by purified insulin receptor.
Type of Immunogen: Cells -
亚型
- IgG1
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应用备注
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Approved: Inhb
Usage: Suitable for use in inhibiting insulin binding. Use antibody at 10nM. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 10 mM PBS, pH 7.4, 0.2 % BSA, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- Insulin Receptor (INSR)
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别名
- INSR / Insulin Receptor
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背景
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Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase
Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen -
基因ID
- 3643
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UniProt
- P06213
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途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
抗原
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