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Ephrin B2 抗体 (AA 328-332)

EFNB2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197418
发货至: 中国
  • 抗原 See all Ephrin B2 (EFNB2) 抗体
    Ephrin B2 (EFNB2)
    抗原表位
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 328-332
    适用
    • 58
    • 35
    • 29
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 4
    • 1
    克隆类型
    • 45
    • 12
    多克隆
    标记
    • 35
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Ephrin B2 antibody is un-conjugated
    应用范围
    • 35
    • 20
    • 14
    • 8
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody AP02708PU detects endogenous levels of total Ephrin-B2 protein.
    纯化方法
    Immunoaffinity Chromatography using epitope-specific immunogen.
    免疫原
    Peptide Sequence around amino acids 328~332 (N-I-Y-Y-K) derived from Human Ephrin-B2.
    Top Product
    Discover our top product EFNB2 Primary Antibody
  • 应用备注
    Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    Ephrin B2 (EFNB2)
    别名
    Ephrin-B2 (EFNB2 产品)
    别名
    EFNB2 antibody, efnb2 antibody, ephrin-B2 antibody, htkl antibody, eplg5 antibody, htk-l antibody, lerk5 antibody, ephrinB2 antibody, efnb2a antibody, MGC68890 antibody, efnb2b antibody, ELF-2 antibody, Epl5 antibody, Eplg5 antibody, Htk-L antibody, LERK-5 antibody, Lerk5 antibody, NLERK-1 antibody, EPLG5 antibody, HTKL antibody, LERK5 antibody, ephrin B2 antibody, ephrin-B2 precursor antibody, ephrin B2 L homeolog antibody, ephrin B2 S homeolog antibody, EFNB2 antibody, efnb2 antibody, efnb2.L antibody, efnb2.S antibody, Efnb2 antibody
    背景
    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP)and also interacts with PRKCABP and GRIP1. This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. Ephrin-B2 also binds EphA4, EphB1, EphB2, EphB3 and EphB4. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.Synonyms: EFNB2, EPH-related receptor tyrosine kinase ligand 5, EPLG5, HTK ligand, HTK-L, HTKL, LERK-5, LERK5
    基因ID
    1948
    NCBI登录号
    NP_004084
    UniProt
    P52799
    途径
    RTK signaling, Regulation of Muscle Cell Differentiation
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