Ephrin B2 抗体 (Tyr316)
Quick Overview for Ephrin B2 抗体 (Tyr316) (ABIN197416)
抗原
See all Ephrin B2 (EFNB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Tyr316
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特异性
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Ephrin-B2 antibody AP02707PU detects endogenous levels of total Ephrin-B2 protein.
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纯化方法
- Immunoaffinity chromatography.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human Ephrin-B2 around the phosphorylation site of tyrosine 316 (P-V-Yp-I-V).
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anti-Ephrin B2 (EFNB2) (C-Term) antibody
EFNB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (AA 28-229) antibodyEFNB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) antibodyEFNB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) antibodyEFNB2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (AA 28-229) antibodyEFNB2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (pTyr330) antibodyEFNB2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) antibodyEFNB2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (AA 28-127) antibodyEFNB2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (AA 157-186) antibodyEFNB2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31411 unconjugated
anti-Ephrin B2 (EFNB2) (Extracellular Domain) antibodyEFNB2 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal PA349-18-4-3 unconjugated
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应用备注
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Suitable for use in in Western blot (1: 500-1: 1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- Ephrin B2 (EFNB2)
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别名
- Ephrin-B2
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背景
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP)and also interacts with PRKCABP and GRIP1. This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. Ephrin-B2 also binds EphA4, EphB1, EphB2, EphB3 and EphB4. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.Synonyms: EFNB2, EPH-related receptor tyrosine kinase ligand 5, EPLG5, HTK ligand, HTK-L, HTKL, LERK-5, LERK5
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基因ID
- 1948
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NCBI登录号
- NP_004084
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UniProt
- P52799
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途径
- RTK signaling, Regulation of Muscle Cell Differentiation
抗原
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