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CDK2 抗体 (Thr160)

This anti-CDK2 antibody is a 兔 多克隆 antibody detecting CDK2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN197286
发货至: 中国

Quick Overview for CDK2 抗体 (Thr160) (ABIN197286)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Thr160

    序列

    T-Y-TP-H-E

    特异性

    This antibody detects endogenous levels of total CDK2 protein.

    纯化方法

    Affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized non-phosphopeptide derived from human CDK2 around the phosphorylation site of threonine160.
  • 应用备注

    Western blot (1: 500 - 1: 1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store (in aliquots) at -20 °C.
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    CDK2

    背景

    Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase

    基因ID

    1017

    NCBI登录号

    NP_001789

    UniProt

    P24941

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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