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Nibrin 抗体 (Ser343)

This anti-Nibrin antibody is a 兔多克隆 antibody detecting Nibrin in WB. Suitable for 人.

Image no. 2 for anti-Nibrin (NBN) (Ser343) antibody (ABIN197200) (Nibrin 抗体 (Ser343))

Image no. 1 for anti-Nibrin (NBN) (Ser343) antibody (ABIN197200) (Nibrin 抗体 (Ser343))

2 images

产品编号 ABIN197200

发货至: 中国

Datasheet as PDF

Quick Overview for Nibrin 抗体 (Ser343) (ABIN197200)

抗原

See all Nibrin (NBN) 抗体

Nibrin (NBN)

适用

94
61
35
2
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

69
7
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1

This Nibrin antibody is un-conjugated

应用范围

104
42
31
29
27
26
22
16
15
12
6
4
2
2
1

Western Blotting (WB)

Discover our top product NBN Primary Antibody

抗原表位
39

15

10

8

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Ser343

特异性

This antibody detects endogenous levels of total p95/NBS1 protein.

纯化方法

Affinity Chromatography using epitope-specific immunogen.

免疫原

The antiserum was produced against synthesized non-phosphopeptide derived from human p95/NBS1 around the phosphorylation site of Serine 343 (S-L-SP-Q-G).
anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7E4C2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E7 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated

anti-Nibrin (NBN) (AA 435-754) antibody
NBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 645-754) antibody
NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 714-745), (C-Term) antibody
NBN 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot: 1/100approx. 1/500. Immunohistochemistry: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody (in aliquots) at -20 °C.
抗原

Nibrin (NBN)

别名

Nibrin

背景

The p95 gene (also known as NBS1 and Nibrin) is a member of the hMre11/hRad50 double-strand break complex (MRN complex). This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions. In case of infection by adenovirus E4, the MRN complex is inactivated and degraded by viral oncoproteins, thereby preventing concatenation of viral genomes in infected cells. NBS1 is expressed ubiquitously and presents high levels in testis.Synonyms: Cell cycle regulatory protein p95, NBN, NBS, NBS1, Nijmegen breakage syndrome protein 1, P95

基因ID

4683

NCBI登录号

NP_002476

UniProt

O60934

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response

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