STAT5A 抗体 (Tyr694)
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Quick Overview for STAT5A 抗体 (Tyr694) (ABIN197180)
抗原
See all STAT5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Tyr694
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特异性
- This antibody detects endogenous levels of total STAT5A around Tyrosine 694.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human STAT5A around the phosphorylation site of Tyrosine 694 (D-G-YP-V-K).
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应用备注
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Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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别名
- STAT5 / STAT5A
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背景
- STAT5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96 % sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.Synonyms: MGF, Mammary gland factor, STAT-5, STAT-5A, Signal transducer and activator of transcription 5A
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基因ID
- 6776
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NCBI登录号
- NP_003143
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UniProt
- P42229
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
抗原
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