PKC theta 抗体 (pSer676)
Our Local Distributor
北京 101111
Quick Overview for PKC theta 抗体 (pSer676) (ABIN197070)
抗原
See all PKC theta (PRKCQ) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer676
-
特异性
- This antibody detects endogenous levels of PKC-theta only when phosphorylated at Serine 676.
-
纯化方法
- Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
-
免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human PKCtheta around the phosphorylation site of serine 676 (R-L-SP-F-A).
-
-
anti-Protein Kinase C, theta (PRKCQ) (pSer676) antibody
PRKCQ 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 380-634) antibodyPRKCQ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 15-294) antibodyPRKCQ 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (pThr538) antibodyPRKCQ 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (C-Term) antibodyPRKCQ 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) antibodyPRKCQ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4105 unconjugated Recombinant Antibody
anti-Protein Kinase C, theta (PRKCQ) (pSer695) antibodyPRKCQ 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 318-348), (C-Term) antibodyPRKCQ 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01242 unconjugated
anti-Protein Kinase C, theta (PRKCQ) (pSer676) antibodyPRKCQ 适用: 人, 大鼠, 小鼠, Cow, 犬, Pig, 猴 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 351-450) antibodyPRKCQ 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody (in aliquots) at -20 °C.
-
-
- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
-
别名
- PRKCQ / PRKCT
-
背景
- Protein kinase C (PKC) is a family of serine/threonine kinases that plays crucial roles in signal transduction. Members of the PKC family are divided into three groups based on their molecular structures and activating mechanisms: 1) Conventional PKC (alpha, beta, and gamma) requiring calcium, phosphatidylserine (PS), and diacylglycerol (DG) for activation, 2) novel PKC (sigma, epsilon, eta, and theta) activated independent of calcium, and 3) Atypical PKC (zeta and lamda), which are independent of both calcium and DG. High-level expression of PKC-theta was found in skeletal muscle, lung, T cells, and brain, and minimal expression in cardiac muscle, placenta, and liver. PKC theta is a autophosphorylated protein kinase.Synonyms: PKC theta, PKC-theta, Protein kinase C theta type, Protein kinase C theta type, nPKC-theta
-
基因ID
- 5588
-
NCBI登录号
- NP_001229342
-
UniProt
- Q04759
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
-
