JAK1 抗体 (pTyr1022)
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- 抗原 See all JAK1 抗体
- JAK1 (Janus Kinase 1 (JAK1))
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抗原表位
- pTyr1022
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JAK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site. JAK1 (phospho-Tyr1022) antibody detects endogenous levels of JAK1 only when phosphorylated at tyrosine 1022.
- 纯化方法
- Immunoaffinity chromatography.
- 免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human JAK1 around the phosphorylation site of tyrosine 1022 (K-E-YP-Y-T).
- Top Product
- Discover our top product JAK1 Primary Antibody
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- 应用备注
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Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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-
Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions." in: Frontiers in immunology, Vol. 11, pp. 344, (2021) (PubMed).
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Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions." in: Frontiers in immunology, Vol. 11, pp. 344, (2021) (PubMed).
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- 抗原
- JAK1 (Janus Kinase 1 (JAK1))
- 别名
- Tyrosine-Protein Kinase JAK1 (JAK1 产品)
- 别名
- JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
- 背景
- Synonyms: JAK-1, JAK1A, JAK1B, Janus kinase 1
- 基因ID
- 3716
- NCBI登录号
- NP_002218
- UniProt
- P23458
- 途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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