电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

JAK1 抗体 (pTyr1022)

JAK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN196868
发货至: 中国
  • 抗原 See all JAK1 抗体
    JAK1 (Janus Kinase 1 (JAK1))
    抗原表位
    • 16
    • 16
    • 10
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1022
    适用
    • 103
    • 82
    • 62
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 83
    • 26
    • 1
    • 1
    克隆类型
    • 82
    • 29
    多克隆
    标记
    • 50
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This JAK1 antibody is un-conjugated
    应用范围
    • 75
    • 38
    • 26
    • 17
    • 16
    • 14
    • 11
    • 11
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site. JAK1 (phospho-Tyr1022) antibody detects endogenous levels of JAK1 only when phosphorylated at tyrosine 1022.
    纯化方法
    Immunoaffinity chromatography.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from human JAK1 around the phosphorylation site of tyrosine 1022 (K-E-YP-Y-T).
    Top Product
    Discover our top product JAK1 Primary Antibody
  • 应用备注
    Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • Fetter, Smith, Guel, Braegelmann, Bieber, Wenzel: "Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions." in: Frontiers in immunology, Vol. 11, pp. 344, (2021) (PubMed).

  • 抗原
    JAK1 (Janus Kinase 1 (JAK1))
    别名
    Tyrosine-Protein Kinase JAK1 (JAK1 产品)
    别名
    JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
    背景
    Synonyms: JAK-1, JAK1A, JAK1B, Janus kinase 1
    基因ID
    3716
    NCBI登录号
    NP_002218
    UniProt
    P23458
    途径
    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
You are here:
客服