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JAK1 抗体 (pTyr1022)

There is 1 publication for this product available. The 兔多克隆 anti-JAK1 antibody is suitable to detect JAK1 in samples from 人, 小鼠和大鼠. It has been validated for WB 和 IHC (p).

Image no. 1 for anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody (ABIN196868) (JAK1 抗体 (pTyr1022))

2 images

(1 reference)

产品编号 ABIN196868

发货至: 中国

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Quick Overview for JAK1 抗体 (pTyr1022) (ABIN196868)

抗原

See all JAK1 抗体

JAK1 (Janus Kinase 1 (JAK1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This JAK1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product JAK1 Primary Antibody

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pTyr1022

特异性

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site. JAK1 (phospho-Tyr1022) antibody detects endogenous levels of JAK1 only when phosphorylated at tyrosine 1022.

纯化方法

Immunoaffinity chromatography.

免疫原

The antiserum was produced against synthesized phosphopeptide derived from human JAK1 around the phosphorylation site of tyrosine 1022 (K-E-YP-Y-T).
anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1023) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) antibody
KD Validated JAK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2245 unconjugated Recombinant Antibody

anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibody
JAK1 适用: 人 WB 宿主: 兔 Polyclonal RB43809 unconjugated

anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibody
JAK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43812 unconjugated

anti-Janus Kinase 1 (JAK1) (Ser639) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) antibody
JAK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated

anti-Janus Kinase 1 (JAK1) antibody
JAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (C-Term) antibody
JAK1 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, Pig WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody (in aliquots) at -20 °C.
Fetter, Smith, Guel, Braegelmann, Bieber, Wenzel: "Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions." in: Frontiers in immunology, Vol. 11, pp. 344, (2021) (PubMed).
抗原

JAK1 (Janus Kinase 1 (JAK1))

别名

Tyrosine-Protein Kinase JAK1

背景

Synonyms: JAK-1, JAK1A, JAK1B, Janus kinase 1

基因ID

3716

NCBI登录号

NP_002218

UniProt

P23458

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response