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CDK2 抗体 (pThr160)

CDK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN196844
发货至: 中国
  • 抗原 See all CDK2 抗体
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    抗原表位
    • 30
    • 27
    • 17
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    • 5
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    • 1
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    • 1
    • 1
    • 1
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    pThr160
    适用
    • 174
    • 97
    • 77
    • 10
    • 10
    • 8
    • 8
    • 6
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    • 6
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    • 5
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    • 2
    人, 小鼠
    宿主
    • 181
    • 17
    • 1
    克隆类型
    • 172
    • 27
    多克隆
    标记
    • 93
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    • 5
    • 5
    • 5
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    This CDK2 antibody is un-conjugated
    应用范围
    • 167
    • 75
    • 52
    • 50
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    • 28
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. CDK2 (phospho-Thr160) antibody detects endogenous levels of CDK2 only when phosphorylated at threonine 160.
    纯化方法
    Immunoaffinity chromatography.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from human CDK2 around the phosphorylation site of threonine 160 (T-Y-TP-H-E).
    Top Product
    Discover our top product CDK2 Primary Antibody
  • 应用备注
    Suitable for use in Western blot (1: 500approx. 1: 1000), ELISA (1: 4000) and Immunohistochemistry(1: 50approx. 1: 100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    别名
    CDK2 (CDK2 产品)
    别名
    p33(CDK2) antibody, A630093N05Rik antibody, wu:fa10c02 antibody, zgc:56598 antibody, zgc:77684 antibody, eg1 antibody, CDKN2 antibody, cdk2L antibody, cyclin dependent kinase 2 antibody, cyclin-dependent kinase 2 antibody, cyclin-dependent kinase 2 S homeolog antibody, CDK2 antibody, Cdk2 antibody, cdk2 antibody, cdk2.S antibody
    背景
    Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase
    基因ID
    1017
    NCBI登录号
    NP_001789
    UniProt
    P24941
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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