CREB1 抗体 (AA 1-297)
Quick Overview for CREB1 抗体 (AA 1-297) (ABIN1944898)
抗原
See all CREB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-297
-
纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
免疫原
- This CREB1 antibody is generated from a mouse immunized with a recombinant protein from human CREB1.
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
- IHC: 1:500. WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
Diversification of cyclic AMP-responsive enhancer binding proteins-generated by alternative exon splicing." in: Transactions of the Association of American Physicians, Vol. 103, pp. 28-37, (1992) (PubMed).
: "Nucleotide and derived amino-acid sequences of the CRE-binding proteins from rat C6 glioma and HeLa cells." in: Nucleic acids research, Vol. 19, Issue 15, pp. 4290, (1991) (PubMed).
: "Two distinct forms of active transcription factor CREB (cAMP response element binding protein)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 14, pp. 5258-62, (1990) (PubMed).
: "Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain." in: The EMBO journal, Vol. 9, Issue 8, pp. 2537-42, (1990) (PubMed).
: "Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA." in: Science (New York, N.Y.), Vol. 242, Issue 4884, pp. 1430-3, (1989) (PubMed).
: "
-
Diversification of cyclic AMP-responsive enhancer binding proteins-generated by alternative exon splicing." in: Transactions of the Association of American Physicians, Vol. 103, pp. 28-37, (1992) (PubMed).
-
- CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
-
别名
- CREB1
-
背景
- Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
-
分子量
- 35136
-
基因ID
- 1385
-
UniProt
- P16220
-
途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
抗原
-