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CREB1 抗体 (AA 1-297)

This 小鼠 单克隆 antibody specifically detects CREB1 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠. It has been mentioned in 5+ publications
产品编号 ABIN1944898
发货至: 中国
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Quick Overview for CREB1 抗体 (AA 1-297) (ABIN1944898)

抗原

See all CREB1 抗体
CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

适用

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人, 小鼠, 大鼠

宿主

  • 266
  • 28
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小鼠

克隆类型

  • 222
  • 74
单克隆

标记

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This CREB1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

1335CT115-203-189
  • 抗原表位

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    AA 1-297

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This CREB1 antibody is generated from a mouse immunized with a recombinant protein from human CREB1.

    亚型

    IgG1 kappa
  • 应用备注

    IHC: 1:500. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Waeber, Meyer, Hoeffler, Habener: "Diversification of cyclic AMP-responsive enhancer binding proteins-generated by alternative exon splicing." in: Transactions of the Association of American Physicians, Vol. 103, pp. 28-37, (1992) (PubMed).

    Short, Manohar, Furtado, Ghadge, Wolinsky, Thimmapaya, Jungmann: "Nucleotide and derived amino-acid sequences of the CRE-binding proteins from rat C6 glioma and HeLa cells." in: Nucleic acids research, Vol. 19, Issue 15, pp. 4290, (1991) (PubMed).

    Berkowitz, Gilman: "Two distinct forms of active transcription factor CREB (cAMP response element binding protein)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 14, pp. 5258-62, (1990) (PubMed).

    Yoshimura, Fujisawa, Yoshida: "Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain." in: The EMBO journal, Vol. 9, Issue 8, pp. 2537-42, (1990) (PubMed).

    Hoeffler, Meyer, Yun, Jameson, Habener: "Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA." in: Science (New York, N.Y.), Vol. 242, Issue 4884, pp. 1430-3, (1989) (PubMed).

  • 抗原

    CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

    别名

    CREB1

    背景

    Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

    分子量

    35136

    基因ID

    1385

    UniProt

    P16220

    途径

    TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
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