CD51 抗体 (Cleaved-Lys889)
Quick Overview for CD51 抗体 (Cleaved-Lys889) (ABIN1944813)
抗原
See all CD51 (ITGAV) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Lys889
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亚型
- IgG1
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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储存条件
- 4 °C,-20 °C
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: "Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51." in: Cytogenetics and cell genetics, Vol. 89, Issue 3-4, pp. 268-71, (2000) (PubMed).
: "Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs." in: The Journal of biological chemistry, Vol. 262, Issue 29, pp. 14080-5, (1987) (PubMed).
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: "Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51." in: Cytogenetics and cell genetics, Vol. 89, Issue 3-4, pp. 268-71, (2000) (PubMed).
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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别名
- ITGAV
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背景
- The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
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分子量
- 116038 Da
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基因ID
- 3685
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UniProt
- P06756
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
抗原
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