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NCF1 抗体

This 兔 多克隆 antibody specifically detects NCF1 in WB 和 IF. It exhibits reactivity toward 人. It has been mentioned in 4+ publications
产品编号 ABIN1944805
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NCF1 抗体 (ABIN1944805)

抗原

See all NCF1 抗体
NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

适用

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  • 48
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宿主

  • 135
  • 1

克隆类型

  • 124
  • 12
多克隆

标记

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This NCF1 antibody is un-conjugated

应用范围

  • 105
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  • 26
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Western Blotting (WB), Immunofluorescence (IF)
  • 亚型

    IgG1
  • 应用备注

    IF: 1:100. WB: 1:250-1:1000. WB: 1:250-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    储存条件

    4 °C,-20 °C
  • Görlach, Lee, Roesler, Hopkins, Christensen, Green, Chanock, Curnutte: "A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease." in: The Journal of clinical investigation, Vol. 100, Issue 8, pp. 1907-18, (1997) (PubMed).

    Rodaway, Teahan, Casimir, Segal, Bentley: "Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid." in: Molecular and cellular biology, Vol. 10, Issue 10, pp. 5388-96, (1990) (PubMed).

    Volpp, Nauseef, Donelson, Moser, Clark: "Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 18, pp. 7195-9, (1989) (PubMed).

    Lomax, Leto, Nunoi, Gallin, Malech: "Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease." in: Science (New York, N.Y.), Vol. 245, Issue 4916, pp. 409-12, (1989) (PubMed).

  • 抗原

    NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

    别名

    p47 phox

    背景

    NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).

    分子量

    44652 Da

    基因ID

    653361

    UniProt

    P14598

    途径

    PI3K-Akt Signaling
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