BBS5 抗体 (AA 108-141)
(2 references)Quick Overview for BBS5 抗体 (AA 108-141) (ABIN1944771)
抗原
See all BBS5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 108-141
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预测反应
- Pr, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This BBS5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-141 amino acids from the Central region of human BBS5.
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亚型
- Ig Fraction
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anti-Bardet-Biedl Syndrome 5 (BBS5) (C-Term) antibody
BBS5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 5 (BBS5) (AA 220-270) antibodyBBS5 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 5 (BBS5) (N-Term) antibodyBBS5 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 斑马鱼, 兔, 犬, 猴, Pig, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 5 (BBS5) (AA 224-317) antibodyBBS5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 5 (BBS5) (AA 1-341) antibodyBBS5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 5 (BBS5) (C-Term) antibodyBBS5 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 兔, 犬, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 5 (BBS5) (N-Term) antibodyBBS5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 5 (BBS5) (N-Term) antibodyBBS5 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).
: "Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene." in: Cell, Vol. 117, Issue 4, pp. 541-52, (2004) (PubMed).
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: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).
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- BBS5 (Bardet-Biedl Syndrome 5 (BBS5))
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别名
- BBS5
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背景
- The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
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分子量
- 38755
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基因ID
- 129880
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UniProt
- Q8N3I7
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途径
- Hedgehog Signaling
抗原
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