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L-Selectin 抗体 (PE)

This anti-L-Selectin antibody is a 小鼠 单克隆 antibody detecting L-Selectin in FACS. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN192343
发货至: 中国

Quick Overview for L-Selectin 抗体 (PE) (ABIN192343)

抗原

See all L-Selectin (SELL) 抗体
L-Selectin (SELL) (Selectin L (SELL))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This L-Selectin antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

LT-TD180
  • 原理

    Anti-Hu CD62L PE

    特异性

    The antibody LT-TD180 reacts with an extracellular epitope of CD62L (L-selectin), a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Peripheral blood leukocytes

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 溶解方式

    No reconstitution is necessary.

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Linnebacher, Wienck, Boeck, Klar: "Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO)." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 841451, (2010) (PubMed).

    Kuttruff, Koch, Kelp, Pawelec, Rammensee, Steinle: "NKp80 defines and stimulates a reactive subset of CD8 T cells." in: Blood, Vol. 113, Issue 2, pp. 358-69, (2009) (PubMed).

    Simone, Zicca, Saverino: "The frequency of regulatory CD3+CD8+CD28- CD25+ T lymphocytes in human peripheral blood increases with age." in: Journal of leukocyte biology, Vol. 84, Issue 6, pp. 1454-61, (2008) (PubMed).

  • 抗原

    L-Selectin (SELL) (Selectin L (SELL))

    别名

    CD62L

    背景

    Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM-1, LECAM1, LEU8, LNHR, LYAM1, PLNHR

    基因ID

    6402

    UniProt

    P14151
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