FASL 抗体 (C-Term)
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北京 101111
Quick Overview for FASL 抗体 (C-Term) (ABIN191900)
抗原
See all FASL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Detects ~31 kDa FasL. A ~70 kDa band, possible represents the FasL and Fas complex, can also be detected.
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纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide mapping to the C-terminus of rat FasL
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应用备注
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Western blotting (0.5-4 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store in aliquots at -20 °C.
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- CD178 / Fas Ligand
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背景
- Fas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
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基因ID
- 14103
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NCBI登录号
- NP_034307
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UniProt
- P41047
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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