PPARG 抗体
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北京 101111
Quick Overview for PPARG 抗体 (ABIN191899)
抗原
See all PPARG 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes a ~33 kDa band, corresponding to PPARgamma isoform CRA-c).
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纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide surrounding amino acid 262 of human PPAR gamma isoform CRA-c
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应用备注
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Western blotting (0.5-4 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
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别名
- PPAR-gamma
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背景
- PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPAR gamma is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism, PPARgamma also modulates insulin sensitivity, cell proliferation and inflammation. The inhibition of PPAR gamma transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARgamma.Synonyms: NR1C3, PPARG, Peroxisome proliferator-activated receptor gamma
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基因ID
- 5468
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NCBI登录号
- NP_005028
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UniProt
- P37231
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途径
- MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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