BNIP3L
适用: 小鼠
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
限制
仅限研究用
状态
Liquid
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
抗原
BNIP3L/NIX (BNIP3L)
(BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
别名
Bnip3L
背景
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain is a potent death domain.BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family.A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3alpha, and Nix (for Nip3-like protein X).Bnip3L/Bnip3alpha/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3.Overexpression of Bnip3L induces apoptosis.Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL.Bnip3L is localized in mitochondria.The messenger RNA of Bnip3L is ubiquitously expressed in human tissues.Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins. Synonyms: Nix