Axin 抗体 (AA 800-862)
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北京 101111
Quick Overview for Axin 抗体 (AA 800-862) (ABIN1886672)
抗原
See all Axin (AXIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 800-862
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 800 and 862 of Human AXIN1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Axin (AXIN1) (Axin 1 (AXIN1))
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别名
- Axin 1
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背景
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This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain.The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself.This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis.The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved.Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas.Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq]
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分子量
- 96 kDa
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基因ID
- 8312
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NCBI登录号
- NP_003493, NM_003502
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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