SSRP1 抗体 (AA 75-308)
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北京 101111
Quick Overview for SSRP1 抗体 (AA 75-308) (ABIN1886647)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-308
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 75 and 308 of SSRP1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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别名
- SSRP1
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背景
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The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT.FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation.FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin.This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA.This protein also functions as a co-activator of the transcriptional activator p63.An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.[provided by RefSeq]
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分子量
- 81 kDa
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基因ID
- 6749
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NCBI登录号
- NM_003146, NP_003137
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途径
- Chromatin Binding
抗原
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