Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250
限制
仅限研究用
状态
Liquid
缓冲液
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
储存液
Thimerosal (Merthiolate)
注意事项
Biohazard Informations: This product contains thimerosal which is hazardous.
储存条件
4 °C/-20 °C
储存方法
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原
SSRP1
(Structure Specific Recognition Protein 1 (SSRP1))
别名
SSRP1
背景
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT.FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation.FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin.This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA.This protein also functions as a co-activator of the transcriptional activator p63.An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.[provided by RefSeq]