Ubiquilin 1 抗体 (AA 64-315)
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北京 101111
Quick Overview for Ubiquilin 1 抗体 (AA 64-315) (ABIN1886597)
抗原
See all Ubiquilin 1 (UBQLN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 64-315
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 315 of Ubiquilin-1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Ubiquilin 1 (UBQLN1)
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别名
- Ubiquilin-1
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背景
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This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog.Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain.They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation.This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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分子量
- 63 kDa
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基因ID
- 29979
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NCBI登录号
- NP_038466, NM_013438
抗原
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