Retinoblastoma Binding Protein 8 抗体 (AA 452-747)
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- 抗原 See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
- Retinoblastoma Binding Protein 8 (RBBP8)
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抗原表位
- AA 452-747
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Retinoblastoma Binding Protein 8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 452 and 747 of CtIP
- Top Product
- Discover our top product RBBP8 Primary Antibody
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- 应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- Retinoblastoma Binding Protein 8 (RBBP8)
- 别名
- CtIP (RBBP8 产品)
- 别名
- COM1 antibody, CTIP antibody, JWDS antibody, RIM antibody, SAE2 antibody, SCKL2 antibody, 9930104E21Rik antibody, CtIP antibody, RBBP-8 antibody, RGD1308872 antibody, RBBP8 antibody, DKFZp469K0714 antibody, RB binding protein 8, endonuclease antibody, retinoblastoma binding protein 8, endonuclease antibody, retinoblastoma binding protein 8 L homeolog antibody, retinoblastoma binding protein 8 antibody, RBBP8 antibody, Rbbp8 antibody, rbbp8.L antibody, rbbp8 antibody
- 背景
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The protein encoded by this gene is a ubiquitously expressed nuclear protein.It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation.This protein complexes with transcriptional co-repressor CTBP.It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control.It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1.Three transcript variants encoding two different isoforms have been found for this gene.More transcript variants exist, but their full-length natures have not been determined.[provided by RefSeq]
- 分子量
- 102 kDa
- 基因ID
- 5932
- NCBI登录号
- NM_002894, NP_002885
- 途径
- Cell Division Cycle, DNA Damage Repair
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