INHBA 抗体 (AA 362-423)
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Quick Overview for INHBA 抗体 (AA 362-423) (ABIN1886407)
抗原
See all INHBA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 362-423
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 362 and 423 of Inhibin beta-A
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- INHBA (Inhibin, beta A (INHBA))
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别名
- Inhibin beta-A
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背景
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The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor.Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity.In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease.Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.[provided by RefSeq]
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分子量
- 47 kDa
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基因ID
- 3624
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NCBI登录号
- NM_002192, NP_002183
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途径
- Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
抗原
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