IL12RB2 抗体 (AA 323-665)
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北京 101111
Quick Overview for IL12RB2 抗体 (AA 323-665) (ABIN1886370)
抗原
See all IL12RB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 323-665
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 323 and 665 of Human IL12RB2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
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背景
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The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex.The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation.The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.[provided by RefSeq]
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分子量
- 97 kDa
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基因ID
- 3595
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NCBI登录号
- NM_001559, NP_001550
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途径
- JAK/STAT Signaling
抗原
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