DMBT1 抗体 (AA 2025-2273)
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北京 101111
Quick Overview for DMBT1 抗体 (AA 2025-2273) (ABIN1886177)
抗原
See all DMBT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2025-2273
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 2025 and 2273 of Human DMBT1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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别名
- gp340
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背景
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Loss of sequences from human chromosome 10q has been associated with the progression of human cancers.The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line.DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized.The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID).Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition.This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.[provided by RefSeq]
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分子量
- 260 kDa
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基因ID
- 1755
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NCBI登录号
- NM_017579, NP_060049
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途径
- Activation of Innate immune Response
抗原
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