PKLR 抗体 (AA 1-230)
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北京 101111
Quick Overview for PKLR 抗体 (AA 1-230) (ABIN1885816)
抗原
See all PKLR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-230
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 230 of Pyruvate Kinase(liver/RBC)
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
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背景
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The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis.Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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分子量
- 62 kDa
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基因ID
- 5313
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NCBI登录号
- NM_000298, NP_000289
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途径
- Ribonucleoside Biosynthetic Process
抗原
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