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SMC1A 抗体 (AA 1-218)

This anti-SMC1A antibody is a 兔 多克隆 antibody detecting SMC1A in WB 和 IHC. Suitable for 人.
产品编号 ABIN1885793
发货至: 中国

Quick Overview for SMC1A 抗体 (AA 1-218) (ABIN1885793)

抗原

See all SMC1A 抗体
SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

适用

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宿主

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克隆类型

  • 99
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多克隆

标记

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This SMC1A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-218

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 218 of SMC1A
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

    别名

    SMC1A

    背景

    Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division.The cohesin multiprotein complex is required for sister chromatid cohesion.This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene.Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain.Therefore, the encoded protein is thought to be an important part of functional kinetochores.In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair.This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.[provided by RefSeq]

    分子量

    143 kDa

    基因ID

    8243

    NCBI登录号

    NP_006297, NM_006306

    途径

    Stem Cell Maintenance
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