SMC1A 抗体 (AA 1-218)
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北京 101111
Quick Overview for SMC1A 抗体 (AA 1-218) (ABIN1885793)
抗原
See all SMC1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-218
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 218 of SMC1A
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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别名
- SMC1A
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背景
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Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division.The cohesin multiprotein complex is required for sister chromatid cohesion.This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene.Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain.Therefore, the encoded protein is thought to be an important part of functional kinetochores.In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair.This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.[provided by RefSeq]
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分子量
- 143 kDa
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基因ID
- 8243
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NCBI登录号
- NP_006297, NM_006306
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途径
- Stem Cell Maintenance
抗原
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