USP22 抗体
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北京 101111
Quick Overview for USP22 抗体 (ABIN1882289)
抗原
See all USP22 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- Purified His-tagged USP22 protein was used to produced this monoclonal antibody.
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亚型
- IgG1
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).
: "The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression." in: Molecular cell, Vol. 29, Issue 1, pp. 102-11, (2008) (PubMed).
: "The expression patterns of deubiquitinating enzymes, USP22 and Usp22." in: Gene expression patterns : GEP, Vol. 6, Issue 3, pp. 277-84, (2006) (PubMed).
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: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).
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- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
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别名
- USP22
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背景
- Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
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分子量
- 59961
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NCBI登录号
- NP_056091
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UniProt
- Q9UPT9
抗原
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