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USP22 抗体

There are 3+ publications for this product available. The 小鼠 单克隆 anti-USP22 antibody is suitable to detect USP22 in samples from 人. It has been validated for WB.
产品编号 ABIN1882289
发货至: 中国
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Quick Overview for USP22 抗体 (ABIN1882289)

抗原

See all USP22 抗体
USP22 (Ubiquitin Specific Peptidase 22 (USP22))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This USP22 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

1154CT13-1-3-1
  • 纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    Purified His-tagged USP22 protein was used to produced this monoclonal antibody.

    亚型

    IgG1
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

    Zhang, Varthi, Sykes, Phillips, Warzecha, Zhu, Wyce, Thorne, Berger, McMahon: "The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression." in: Molecular cell, Vol. 29, Issue 1, pp. 102-11, (2008) (PubMed).

    Lee, Kim, Shin, Park, Chung, Baek: "The expression patterns of deubiquitinating enzymes, USP22 and Usp22." in: Gene expression patterns : GEP, Vol. 6, Issue 3, pp. 277-84, (2006) (PubMed).

  • 抗原

    USP22 (Ubiquitin Specific Peptidase 22 (USP22))

    别名

    USP22

    背景

    Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

    分子量

    59961

    NCBI登录号

    NP_056091

    UniProt

    Q9UPT9
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