This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
免疫原
This CYK18 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 400-430 region of human CYK18.
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
Kulesh, Oshima: "Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells." in: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1540-50, (1988) (PubMed).
Oshima, Millán, Ceceña: "Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation." in: Differentiation; research in biological diversity, Vol. 33, Issue 1, pp. 61-8, (1987) (PubMed).
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背景
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.