ATG4C 抗体 (C-Term)
(3 references)Quick Overview for ATG4C 抗体 (C-Term) (ABIN1882160)
抗原
See all ATG4C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 419-448, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This ATG4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the C-terminal region of human ATG4C.
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亚型
- Ig Fraction
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anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 321-458) antibody
ATG4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10H7 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 419-448) antibodyATG4C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibodyATG4C 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 167-196) antibodyATG4C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7497 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 33-62), (N-Term) antibodyATG4C 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7561 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 259-458) antibodyATG4C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 1-458) antibodyATG4C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 21-70) antibodyATG4C 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibodyATG4C 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (C-Term) antibodyVerified ATG4C 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Temporal orchestration of circadian autophagy rhythm by C/EBP?." in: The EMBO journal, Vol. 30, Issue 22, pp. 4642-51, (2012) (PubMed).
: "The in vitro cleavage of the hAtg proteins by cell death proteases." in: Autophagy, Vol. 6, Issue 8, pp. 1042-56, (2010) (PubMed).
: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).
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: "Temporal orchestration of circadian autophagy rhythm by C/EBP?." in: The EMBO journal, Vol. 30, Issue 22, pp. 4642-51, (2012) (PubMed).
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- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
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别名
- ATG4C
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
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分子量
- 52497
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NCBI登录号
- NP_116241, NP_835739
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UniProt
- Q96DT6
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途径
- Autophagy
抗原
-
