电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ATG3 抗体 (C-Term)

This anti-ATG3 antibody is a 兔 多克隆 antibody detecting ATG3 in WB. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1882157
发货至: 中国

Quick Overview for ATG3 抗体 (C-Term) (ABIN1882157)

抗原

See all ATG3 抗体
ATG3 (ATG3 Autophagy Related 3 (ATG3))

适用

  • 88
  • 40
  • 39
  • 7
  • 7
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 89
  • 13
  • 3

克隆类型

  • 83
  • 22
多克隆

标记

  • 44
  • 8
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This ATG3 antibody is un-conjugated

应用范围

  • 73
  • 43
  • 26
  • 26
  • 17
  • 11
  • 10
  • 10
  • 7
  • 6
  • 4
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB7459
  • 抗原表位

    • 15
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 168-197, C-Term

    预测反应

    B

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ATG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human ATG3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Radoshevich, Murrow, Chen, Fernandez, Roy, Fung, Debnath: "ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death." in: Cell, Vol. 142, Issue 4, pp. 590-600, (2010) (PubMed).

    Shintani, Klionsky: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).

  • 抗原

    ATG3 (ATG3 Autophagy Related 3 (ATG3))

    别名

    ATG3

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.

    分子量

    35864

    NCBI登录号

    NP_001265641, NP_071933

    UniProt

    Q9NT62

    途径

    Autophagy
You are here:
Chat with us!