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STAM 抗体 (N-Term)

STAM 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB4633 unconjugated
产品编号 ABIN1882134
发货至: 中国
  • 抗原 See all STAM 抗体
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    抗原表位
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 41
    • 16
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 38
    • 5
    • 1
    • 1
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 33
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STAM antibody is un-conjugated
    应用范围
    • 32
    • 17
    • 17
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This STAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human STAM.
    克隆位点
    RB4633
    亚型
    Ig Fraction
    Top Product
    Discover our top product STAM Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Ortiz, Lee, Smith, Forman, Lee, Liu: "Comparative analyses of differentially induced T-cell receptor-mediated phosphorylation pathways in T lymphoma cells." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 12, pp. 1450-63, (2010) (PubMed).

  • 抗原
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    别名
    STAM (STAM 产品)
    背景
    Stimulation of cells with cytokines initiates a signal transduction cascade involving cytokine receptors, Janus kinases (JAKs) and signal transducers and activators of transcription (STATs). STAM for 'signal-transducing adaptor molecule, induced after stimulation of cells with cytokine IL2, is a component of signal transduction downstream of JAK3.1 Human STAM cDNA cloned from a T-cell cDNA library encodes a 540-amino acid protein precipitated by anti-phosphotyrosine. Northern blot analysis indicates that STAM is expressed as a 2.9-kb message in a wide variety of tissue and cell types. The STAM sequence contains a Src-homology 3 (SH3) domain and an immunoreceptor tyrosine-based activation motif (ITAM). It has been suggested that STAM acts as an adaptor molecule in signal transduction pathways from cytokine receptors.
    分子量
    59180
    NCBI登录号
    NP_003464
    UniProt
    Q92783
    途径
    EGFR Signaling Pathway, EGFR Downregulation
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