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STAM 抗体 (C-Term)

STAM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04604 unconjugated
产品编号 ABIN388974
发货至: 中国
  • 抗原 See all STAM 抗体
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    抗原表位
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 326-356, C-Term
    适用
    • 48
    • 19
    • 9
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 45
    • 5
    • 1
    • 1
    克隆类型
    • 49
    • 3
    多克隆
    标记
    • 35
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STAM antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 21
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This STAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-356 amino acids from the C-terminal region of human STAM.
    克隆位点
    RB04604
    亚型
    Ig Fraction
    Top Product
    Discover our top product STAM Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    别名
    STAM (STAM 产品)
    别名
    STAM-1 antibody, STAM1 antibody, wu:fv75b10 antibody, zgc:55725 antibody, RGD1564499 antibody, signal transducing adaptor molecule antibody, signal transducing adapter molecule 1 antibody, Signal transducing adapter molecule 1 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 antibody, STAM antibody, CpipJ_CPIJ003516 antibody, Tsp_03939 antibody, stam-1 antibody, Stam antibody, stam antibody
    背景
    Stimulation of cells with cytokines initiates a signal transduction cascade involving cytokine receptors, Janus kinases (JAKs) and signal transducers and activators of transcription (STATs). STAM for 'signal-transducing adaptor molecule, induced after stimulation of cells with cytokine IL2, is a component of signal transduction downstream of JAK3.1 Human STAM cDNA cloned from a T-cell cDNA library encodes a 540-amino acid protein precipitated by anti-phosphotyrosine. Northern blot analysis indicates that STAM is expressed as a 2.9-kb message in a wide variety of tissue and cell types. The STAM sequence contains a Src-homology 3 (SH3) domain and an immunoreceptor tyrosine-based activation motif (ITAM). It has been suggested that STAM acts as an adaptor molecule in signal transduction pathways from cytokine receptors.
    分子量
    59180
    基因ID
    8027
    NCBI登录号
    NP_003464
    UniProt
    Q92783
    途径
    EGFR Signaling Pathway, EGFR Downregulation
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