Ret Proto-Oncogene 抗体
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北京 101111
Quick Overview for Ret Proto-Oncogene 抗体 (ABIN1882126)
抗原
See all Ret Proto-Oncogene (RET) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This RET antibody is generated from rabbits immunized with His fusion protein of human RET.
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亚型
- Ig Fraction
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anti-Ret Proto-Oncogene (RET) (AA 702-848) antibody
RET 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal RET-2795 unconjugated
anti-Ret Proto-Oncogene (RET) (AA 1-1072) antibodyRET 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (AA 702-848) antibodyRET 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal RET-2663 unconjugated
anti-Ret Proto-Oncogene (RET) (AA 541-553), (Extracellular) antibodyRET 适用: 人 WB, IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (pTyr1062) antibodyRET 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (C-Term) antibodyRET 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (AA 361-458) antibodyRET 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Ret Proto-Oncogene (RET) (pTyr905) antibodyRET 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (AA 1001-1114) antibodyRET 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (AA 29-300) antibodyRET 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "The RET polymorphic allele S836S is associated with early metastatic disease in patients with hereditary or sporadic medullary thyroid carcinoma." in: Endocrine-related cancer, Vol. 17, Issue 4, pp. 953-63, (2010) (PubMed).
: "Achalasia: will genetic studies provide insights?" in: Human genetics, Vol. 128, Issue 4, pp. 353-64, (2010) (PubMed).
: "A study of RET proto-oncogene polymorphisms in association with lung cancer risk in the Korean population." in: Anticancer research, Vol. 30, Issue 9, pp. 3621-7, (2010) (PubMed).
: "Medullary thyroid carcinoma." in: Clinical oncology (Royal College of Radiologists (Great Britain)), Vol. 22, Issue 6, pp. 475-85, (2010) (PubMed).
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: "The RET polymorphic allele S836S is associated with early metastatic disease in patients with hereditary or sporadic medullary thyroid carcinoma." in: Endocrine-related cancer, Vol. 17, Issue 4, pp. 953-63, (2010) (PubMed).
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- Ret Proto-Oncogene (RET)
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别名
- RET
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背景
- This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
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分子量
- 124319
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NCBI登录号
- NP_065681, NP_066124
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UniProt
- P07949
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途径
- RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
抗原
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