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HSPD1 抗体 (C-Term)

Cited in 4+ publications. This 兔 多克隆 anti-HSPD1 antibody (Clone RB17657) specifically detects HSPD1 in WB, FACS 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1882094
发货至: 中国
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Quick Overview for HSPD1 抗体 (C-Term) (ABIN1882094)

抗原

See all HSPD1 抗体
HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This HSPD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB17657
  • 抗原表位

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    AA 396-423, C-Term

    预测反应

    B, C, Ha, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This HSPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the C-terminal region of human HSPD1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Aboulaich, Vainonen, Strålfors, Vener: "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes." in: The Biochemical journal, Vol. 383, Issue Pt 2, pp. 237-48, (2004) (PubMed).

    Hansen, Bross, Westergaard, Nielsen, Eiberg, Børglum, Mogensen, Kristiansen, Bolund, Gregersen: "Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter." in: Human genetics, Vol. 112, Issue 1, pp. 71-7, (2002) (PubMed).

    Rasmussen, Ji, Eddes, Moritz, Reid, Simpson, Dorow: "Two-dimensional electrophoretic analysis of human breast carcinoma proteins: mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2." in: Electrophoresis, Vol. 18, Issue 3-4, pp. 588-98, (1997) (PubMed).

    Venner, Singh, Gupta: "Nucleotide sequences and novel structural features of human and Chinese hamster hsp60 (chaperonin) gene families." in: DNA and cell biology, Vol. 9, Issue 8, pp. 545-52, (1991) (PubMed).

  • 抗原

    HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

    别名

    HSPD1

    背景

    HSPD1 is a member of the chaperonin family. This protein may function as a signaling molecule in the innate immune system. The protein is essential for the folding and assembly of newly imported proteins in the mitochondria. The protein is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter.

    分子量

    61055

    NCBI登录号

    NP_002147, NP_955472

    UniProt

    P10809

    途径

    Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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