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YBX1 抗体 (AA 149-178)

This anti-YBX1 antibody is a 兔 多克隆 antibody detecting YBX1 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1882002
发货至: 中国

Quick Overview for YBX1 抗体 (AA 149-178) (ABIN1882002)

抗原

See all YBX1 抗体
YBX1 (Y Box Binding Protein 1 (YBX1))

适用

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宿主

  • 91
  • 32

克隆类型

  • 82
  • 41
多克隆

标记

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  • 1
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This YBX1 antibody is un-conjugated

应用范围

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  • 25
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  • 9
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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

RB41913
  • 抗原表位

    • 25
    • 8
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    • 3
    • 2
    • 2
    • 2
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    • 2
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    • 1
    • 1
    • 1
    AA 149-178

    预测反应

    B, M, Rb, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This YBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the Central region of human YBX1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Osada, Uno, Mineta, Kameoka, Takahashi, Terao: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).

    Yu, Yip, Tan, Thike, Matsumoto, Tsujimoto, Bay: "Y-box binding protein 1 is up-regulated in proliferative breast cancer and its inhibition deregulates the cell cycle." in: International journal of oncology, Vol. 37, Issue 2, pp. 483-92, (2010) (PubMed).

    Lovett, Cheng, Cape, Pollock, Mertens: "YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis." in: Biochemical and biophysical research communications, Vol. 398, Issue 3, pp. 482-8, (2010) (PubMed).

    Takahashi, Shimajiri, Izumi, Hirano, Kashiwagi, Yasuniwa, Wu, Han, Akiyama, Nishizawa, Sasaguri, Kohno: "Y-box binding protein-1 is a novel molecular target for tumor vessels." in: Cancer science, Vol. 101, Issue 6, pp. 1367-73, (2010) (PubMed).

    To, Fotovati, Reipas, Law, Hu, Wang, Astanehe, Davies, Lee, Stratford, Raouf, Johnson, Berquin, Royer, Eaves, Dunn: "Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance." in: Cancer research, Vol. 70, Issue 7, pp. 2840-51, (2010) (PubMed).

  • 抗原

    YBX1 (Y Box Binding Protein 1 (YBX1))

    别名

    YBX1

    背景

    Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability.

    分子量

    35924

    NCBI登录号

    NP_004550

    UniProt

    P67809

    途径

    Regulation of Muscle Cell Differentiation
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