YBX1 抗体 (AA 149-178)
Quick Overview for YBX1 抗体 (AA 149-178) (ABIN1882002)
抗原
See all YBX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 149-178
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预测反应
- B, M, Rb, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This YBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the Central region of human YBX1.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).
: "Y-box binding protein 1 is up-regulated in proliferative breast cancer and its inhibition deregulates the cell cycle." in: International journal of oncology, Vol. 37, Issue 2, pp. 483-92, (2010) (PubMed).
: "YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis." in: Biochemical and biophysical research communications, Vol. 398, Issue 3, pp. 482-8, (2010) (PubMed).
: "Y-box binding protein-1 is a novel molecular target for tumor vessels." in: Cancer science, Vol. 101, Issue 6, pp. 1367-73, (2010) (PubMed).
: "Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance." in: Cancer research, Vol. 70, Issue 7, pp. 2840-51, (2010) (PubMed).
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: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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别名
- YBX1
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背景
- Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability.
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分子量
- 35924
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NCBI登录号
- NP_004550
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UniProt
- P67809
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途径
- Regulation of Muscle Cell Differentiation
抗原
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