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STAT1 抗体 (C-Term)

Name: STAT1 抗体 (C-Term)
SKU: ABIN1881847
Availability: OutOfStock

This anti-STAT1 antibody is a 兔多克隆 antibody detecting STAT1 in WB, IHC (p), IF 和 FACS. Suitable for 人. This Primary Antibody has been cited in 4+ publications.

All lanes : Anti-STAT1 Antibody (C-term) at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: A431 whole cell lysate Lane 4: Daudi whole cell lysate Lane 5: Hela whole cell lysate Lane 5: MCF-7 whole cell lysate Lane 5: HT-29 whole cell lysate Lysates/proteins at 20 μg per lane. (STAT1 抗体 (C-Term))

Immunohistochemical analysis of paraffin-embedded human brain tissue using (ABIN1881847 and ABIN2838812) performed on the Leica® BOND RXm. (STAT1 抗体 (C-Term))

IHC (p)

Immunofluorescent analysis of 4 % paraformaldehyde-fixed, 0. (STAT1 抗体 (C-Term))

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using (ABIN1881847 and ABIN2838812) performed on the Leica® BOND RXm. (STAT1 抗体 (C-Term))

IHC (p)

Immunohistochemical analysis of paraffin-embedded human lymph node tissue using (ABIN1881847 and ABIN2838812) performed on the Leica® BOND RXm. (STAT1 抗体 (C-Term))

IHC (p)

Overlay histogram showing Hela cells stained with (ABIN1881847 and ABIN2838812)(green line). (STAT1 抗体 (C-Term))

FACS

6 images

(4 references)

产品编号 ABIN1881847

发货至: 中国

Datasheet as PDF

Quick Overview for STAT1 抗体 (C-Term) (ABIN1881847)

抗原

See all STAT1 抗体

STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This STAT1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RB41406

Discover our top product STAT1 Primary Antibody

抗原表位
45

32

15

12

8

8

6

5

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 717-745, C-Term

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This STAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-745 amino acids from the C-terminal region of human STAT1.

亚型

Ig Fraction
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 343-602) antibody
STAT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibody
STAT1 适用: 人, 犬, 猴 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 4H9 unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibody
STAT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 513-712) antibody
STAT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 650-750) antibody
STAT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibody
STAT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibody
STAT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) antibody
STAT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated

应用备注

IF: 1:25. WB: 1:1000. IHC-P-Leica: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500. FC: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Yang, Shen, Xu, Yang, Tsai, Keng, Chen, Lee: "Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition." in: Scientific reports, Vol. 7, Issue 1, pp. 7958, (2017) (PubMed).

Clarke, Clifford, Jindarat, Proud, Pang, Belvisi, Knox: "TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29101-10, (2010) (PubMed).

Sakamoto, Qin, Navarro, Gamero, Potla, Yi, Zhu, Baker, Feldman, Larner: "Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells." in: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3245-53, (2004) (PubMed).

Zhang, Cho, Petersen, Zhu, Dong: "Evidence of STAT1 phosphorylation modulated by MAPKs, MEK1 and MSK1." in: Carcinogenesis, Vol. 25, Issue 7, pp. 1165-75, (2004) (PubMed).
抗原

STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

别名

STAT1

背景

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

分子量

87335

NCBI登录号

NP_009330, NP_644671

UniProt

P42224

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events